What is MTHFR?

MTHFR or Methylenetetrahydrofolate Reductase is a gene which produces an enzyme known as MTHFR. This enzyme plays a major role in the detoxification and methylation systems and is necessary in processing amino acids into proteins and converting important nutrients such as folate into its active form. Having a genetic mutation in the MTHFR gene can prevent the mitochondria from creating enough energy to send to the entire body. When the brain doesn’t receive enough energy then focus issues and hyperactivity can occur in children.  MTHFR also plays a major role in the detoxification system, and when this system is inefficient toxins start to build up in the gut and create inflammation.

MTHFR mutations also affect the methylation system which is necessary for turning genes on and off. If the body has the inability to turn off the gene that’s creating excess neurotransmitters, such as adrenaline, and the inability to turn on the gene that allows the breakdown of this neurotransmitter, then the body won’t be able to relax and will constantly feel stressed and anxious. For children, these excess neurotransmitters create hyperactivity, irritability, and focus issues.

Your child might have MTHFR if they display these symptoms:

• Focus issues
• Hyperactivity
• Anxiety
• Strong aversion to smells
• Fidgets
• Irritability
• Mood swings
• Impulsive
• Forgetful
• Problems paying attention
• Learning disability
• Depression
• Skin problems: eczema, rashes, irritation
• Allergies/Asthma

The First Step

Fortunately, for children with MTHFR mutations that are displaying ADHD like symptoms, these symptoms can disappear by incorporating the proper nutrients and lifestyle changes. The first step is discovering whether your child has this mutation and which type. The two most common MTHFR mutations are known as MTHFR C677T and MTHFR A1298C. Each mutation and the amount of copies displayed in the child’s genetics changes the effectiveness of the methylation system and the symptoms shown. Therefore, it’s important to find out which mutation your child has and the best diet and nutritional changes to make for the specific mutation.

The easiest way to test your child for an MTHFR mutation is by purchasing an at-home test for the C677T and A1298C MTHFR mutations. At BodyScience, we offer an at home test, that uses a cheek buccal swab for maximum effectiveness. Our results clearly explain which form of the MTHFR mutation you have along with the vitamins and supplements you need. Our MTHFR test kit can be found here.

Want to find out what your specific MTHFR mutation means for you? Take our survey